Application of codon usage and context analysis in genes up- or down-regulated in neurodegeneration and cancer to combat comorbidities.

Rekha Khandia,Megha Katare Pandey,Magdi E A Zaki,Sami A Al-Hussain,Igor Baklanov,Pankaj Gurjar

Frontiers in molecular neuroscience（2023）

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摘要

Using advanced gene editing tools such as CRISPR/Cas or any other gene augmentation technique, these recoded genes may be introduced into the human body to optimize gene expression levels to augment neurodegeneration and cancer therapeutic regimens simultaneously.

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关键词

codon usage,codon pattern,synonymous codons,neurodegeneration,cancer,CRISPR/Cas

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