Nasal shedding of vaccine viruses after immunization with a Russian-backbone live attenuated influenza vaccine in India.

Lalit Dar,Anand Krishnan,Ramesh Kumar,Shivram Dhakad,Avinash Choudekar,Sumedha Bagga,Amrit Sharma, Amit Kumar,Jyoti Jethani,Siddhartha Saha,Ritvik Amarchand,Rakesh Kumar,Aashish Choudhary,Venkatesh Vinayak Narayan,Giridara Gopal,Kathryn E Lafond,Stephen Lindstrom

Influenza and other respiratory viruses（2023）

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摘要

At day 2 post-vaccination in year 1, two-thirds of LAIV recipients were shedding vaccine viruses. Shedding of vaccine viruses varied between strains and was lower in year 2. More research is needed to determine the reason for lower virus shedding and vaccine efficacy for LAIV-A(H1N1)pdm09.

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influenza vaccine,vaccine viruses,immunization,nasal

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