Acquired Factor XIII Deficiency Is Common during ECMO Therapy and Associated with Major Bleeding Events and Transfusion Requirements.

Matthias Noitz,Roxane Brooks,Johannes Szasz, Dennis Jenner,Carl Böck, Niklas Krenner,Martin W Dünser,Jens Meier

Journal of clinical medicine（2023）

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摘要

In this retrospective single centre study, acquired factor XIII deficiency was observed in 69% of adult ECMO patients with a high bleeding risk. Factor XIII deficiency was associated with higher rates of major bleeding events and transfusion requirements.

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关键词

ECMO, factor XIII, deficiency, bleeding, red blood cells, transfusion

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