The presence of preoperative neurodegeneration biofluid markers in patients with postoperative delirium.
Anesthesiology(2023)
摘要
These results suggest that patients who subsequently developed delirium are more likely to be experiencing clinically silent neurodegenerative changes before surgery, reflected by changes in plasma NfL biomarker concentrations, which may identify individuals with a preoperative vulnerability to subsequent cognitive decline.
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