A Tumor Suppressive Role of CYLD as a Novel Potential DUB of Aurora B in Cervical Cancer.

Yufan Huang,Wei Zhang,Zhihui Yu,Hongkai Su, Bin Zeng,Jinsong Piao,Jing Wang,Juan Wu

Clinical Medicine Insights. Oncology（2023）

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摘要

Our findings uncover CYLD as a novel potential DUB of Aurora B, which inhibits Aurora B activation and its subsequent function in cell mitosis, and also provide more evidence for its tumor suppressor function in cervical cancer.

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关键词

Aurora B, CYLD, deubiquitination enzyme, tumor suppressor, cervical cancer

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