Low-molecular-weight heparin therapy reduces 28-day mortality in patients with sepsis-3 by improving inflammation and coagulopathy.

Ze Zhang,Taotao Yan,Danfeng Ren,Jingwen Zhou, Liangru Liu,Juan Li,Shan Fu,Tianzhi Ni,Weicheng Xu,Yuan Yang,Tianyan Chen,Yingli He,Yingren Zhao,Jinfeng Liu

Frontiers in medicine（2023）

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摘要

Our study results showed that LMWH improves 28-day mortality by improving inflammatory response and coagulopathy in patients meeting Sepsis-3 criteria. The SIC and ISTH overt DIC scoring systems can better identify septic patients who are likely to benefit more from LMWH administration.

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关键词

low-molecular-weight heparin, disseminated intravascular coagulation, sepsis, mortality, propensity score

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