Autophagy gene Atg7 regulates the development of radiation-induced skin injury and fibrosis of skin.
Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)（2023）
摘要
In conclusion, Atg7 and autophagy-related mechanisms confer radioprotection, and reactivation of the autophagy process can be a novel therapeutic strategy to reduce and prevent the occurrence of radiodermatitis, particularly skin fibrosis, in patients with cancer.
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关键词
autophagy, fibrosis, oxidative stress, radiodermatitis, rapamycin
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