Novel EAAT2 activators improve motor and cognitive impairment in a transgenic model of Huntington's disease.

Akanksha Bhatnagar,Visha Parmar, Nicholas Barbieri,Frank Bearoff,Felice Elefant,Sandhya Kortagere

Frontiers in behavioral neuroscience（2023）

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摘要

Together, these results highlight the efficacy of GT951, GTS467 and GTS551 in treating motor and cognitive impairments under HD pathology and support their development for treatment of HD.

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关键词

cognitive impairment,huntingtons,transgenic model

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