Endothelial glycocalyx injury is involved in heatstroke-associated coagulopathy and protected by N-acetylcysteine.

Na Peng,Yan Geng,Jiafu Ouyang, Shuai Liu,Fangfang Yuan,Yantong Wan, Wenda Chen,Baojun Yu,Youqing Tang,Lei Su,Huaping Liang,Jiang Huai Wang,Jinghua Liu

Frontiers in immunology（2023）

引用 0|浏览6

暂无评分

摘要

Our results indicate that the poor prognosis of HS patients correlates with severe coagulation disorders, coagulation abnormalities in HS rats are associated with the damage of EGCX, and NAC improves HS-induced coagulopathy, probably through its protection against EGCX injury by preventing ROS generation.

查看译文

关键词

coagulopathy, endothelial glycocalyx, heat stroke, hyaluronic acid, N-acetylcysteine, syndecan-1

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要