Clinical Characteristics and Responses to Immune Checkpoint Inhibitors in RET-Aberrant Digestive Tract Tumours.

Chih-Chieh Yen,Yu-Min Yeh,Hsuan-Yi Huang,Yu-Lin Ting,Pei-An Fu,Tzu-Chien Lin,I-Ting Liu,Chia-Jui Yen

Targeted oncology（2023）

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摘要

Albeit rarely, RET aberrations can be found in digestive tract tumours. Patients with RET-aberrant tumours have a blunted response to ICPi and a comparable prognosis as compared with RET-wild type tumours. Together, these results provide insights into this rare but potentially actionable target in digestive tract tumours.

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关键词

immune checkpoint inhibitors,tumours,ret-aberrant

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