Factors Predictive of Primary Resistance to Immune Checkpoint Inhibitors in Patients with Advanced Non-Small Cell Lung Cancer.

Yiqing Huang,Joseph J Zhao,Yu Yang Soon,Adrian Kee,Sen Hee Tay,Folefac Aminkeng,Yvonne Ang,Alvin S C Wong,Lavina D Bharwani,Boon Cher Goh,Ross A Soo

Cancers（2023）

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摘要

Using SITC criteria, an elevated NLR (≥3) at 6 weeks, female gender and a later line of immunotherapy treatment (≥2 lines) were predictive factors of developing primary resistance to ICI monotherapy in patients with advanced NSCLC.

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关键词

primary resistance, immune checkpoint inhibitor, non-small-cell lung cancer

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