Metformin Versus Insulin and Risk of Major Congenital Malformations in Pregnancies With Type 2 Diabetes: A Nordic Register-Based Cohort Study.

Lars J Kjerpeseth,Carolyn E Cesta,Kari Furu,Anders Engeland,Mika Gissler,Hanne L Gulseth,Øystein Karlstad,Maarit K Leinonen,Laura Pazzagli,Helga Zoega,Jacqueline M Cohen

Diabetes care（2023）

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摘要

No evidence of an increased malformation risk with metformin versus insulin in the first trimester was found. Results should be interpreted with caution since information on glycemic control was missing.

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关键词

metformin,major congenital malformations,insulin,diabetes,pregnancies,register-based

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