Multiplexed bead-based assay for the simultaneous quantification of human serum IgG antibodies to tetanus, diphtheria, pertussis toxin, filamentous hemagglutinin, and pertactin.

Vishal Rathod,Laxmikant Kadam,Manish Gautam, Prabhu Dasu Gumma, Kevin Marke, Cathy Asokanathan, Alex Douglas-Bardsley, Laura Hassell, Sachin Bhandare, Sumit Gupta,Sameer Parekh,Pramod Pujari,Harish Rao,Hitt Sharma,Umesh Shaligram,Sunil Gairola

Frontiers in immunology（2023）

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摘要

The MIA that was calibrated in accordance with WHO reference standards demonstrated increased sensitivity, reproducibility, and high throughput capabilities, allowing for the design of robust studies that evaluate both natural and vaccine-induced immunity.

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关键词

human serum igg,pertussis toxin,antibodies,filamentous hemagglutinin,assay,bead-based

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