A multicenter, phase 1, dose escalation clinical trial (G-FORCE-1) of XRT, RRx-001 and temozolomide followed by temozolomide +/- RRx-001 in newly diagnosed glioblastoma.

Frontiers in oncology(2023)

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摘要
The addition of RRx-001 to TMZ and RT and to TMZ during maintenance was safe and well-tolerated and deserves further study.
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关键词
RRx-001, primary GBM, brain penetrant, hypoxia activated, radiotherapy, temozolomide (not in MeSH)
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