Exploration of the optimal GS-441524 trough concentration for treating COVID-19.

Yuki Nakano, Yoko Inokuchi,Tadashi Hayama,Toshinori Hirai, Mamoru Nishiyama, Yoshiko Sueyasu,Kenjo Yokoo

International journal of antimicrobial agents（2023）

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摘要

GS-441524 trough concentration ≥70 ng/mL is a predictor of efficacy in COVID-19 pneumonia. The presence of lower eGFR or BMI ≥25 kg/m was associated with achieving GS-441524 trough concentration ≥70 ng/mL.

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关键词

Remdesivir, GS-441524, Trough concentration, SARS-CoV-2, COVID-19

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