Dysfunction of basal ganglia functional connectivity associated with subjective and cognitive fatigue in multiple sclerosis.

Christelle Langley,Naoki Masuda, Simon Godwin,Giovanni De Marco,Angela Davies Smith,Rosemary Jones,Jared Bruce,Ngoc Jade Thai

Frontiers in neuroscience（2023）

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摘要

The current study is the first to show that basal ganglia functional connectivity is associated with both subjective and objective fatigue in MS. In addition, the local FC of the basal ganglia during fatigue inducing tasks could provide a neurophysiological biomarker of fatigue.

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关键词

cognitive fatigue,multiple sclerosis,basal ganglia,functional connectivity

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