Spinal neuromodulation mitigates myocardial ischemia-induced sympathoexcitation by suppressing the intermediolateral nucleus hyperactivity and spinal neural synchrony.

Siamak Salavatian,Yuki Kuwabara,Benjamin Wong,Jonathan R Fritz,Kimberly Howard-Quijano,Robert D Foreman,J Andrew Armour, Jeffrey L Ardell,Aman Mahajan

Frontiers in neuroscience（2023）

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摘要

These results suggest that SCS is decreasing the sympathoexcitation and arrhythmogenicity by suppressing the interactions between the spinal DH and IML neurons and activity of IML preganglionic sympathetic neurons.

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关键词

spinal cord stimulation, neuromodulation, myocardial ischemia, autonomic nervous system, arrhythmias, spinal neural network

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