Longitudinal Associations Between Blood Biomarkers and White-Matter MRI in Sport-Related Concussion: A Study of the NCAA-DoD CARE Consortium.

This prospective study using data from the CARE Consortium demonstrated that in the early phase of SRC, white-matter microstructural integrity detected by DTI neuroimaging was associated with elevated levels of blood-based biomarkers of traumatic brain injury. Total tau in the blood showed the strongest association with white-matter microstructural changes.