Study protocol of IMAGINE-HD: Imaging iron accumulation and neuroinflammation with 7T-MRI + CSF in Huntington's disease.

Nadine Anniek van de Zande,Marjolein Bulk,Chloé Najac,Louise van der Weerd,Jeroen de Bresser,Jan Lewerenz,Itamar Ronen,Susanne Tamara de Bot

NeuroImage. Clinical（2023）

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摘要

Results from this study will provide an important basis for the evaluation of brain iron levels and neuroinflammation metabolites as an imaging biomarker for disease stage in HD and their relationship with the salient pathomechanisms of the disease on the one hand, and with clinical outcome on the other.

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关键词

neuroinflammation,huntingtons,iron accumulation,imaging,t-mri

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