Comparative efficacy and safety of multitarget angiogenesis inhibitor combined with immune checkpoint inhibitor and nivolumab monotherapy as second-line or beyond for advanced lung adenocarcinoma in driver-negative patients: a retrospective comparative cohort study.

Translational lung cancer research(2023)

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摘要
The combination of the multitargeting tyrosine kinase inhibitor anlotinib and PD-1 blockade demonstrated significant benefits as the second- and subsequent-line treatment in driver-negative patients with advanced LUAD, even in those who underwent previous immunotherapy.
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关键词
multitarget angiogenesis inhibitor,advanced lung adenocarcinoma,immune checkpoint inhibitor,nivolumab monotherapy,second-line,driver-negative
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