The Emergence and Progression of Motor Dysfunction in Individuals at Risk of Parkinson's Disease.

Cristina Simonet,Philipp Mahlknecht,Kathrin Marini,Klaus Seppi,Aneet Gill,Jonathan P Bestwick,Andrew J Lees,Gavin Giovannoni,Anette Schrag,Alastair J Noyce

Movement disorders : official journal of the Movement Disorder Society（2023）

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摘要

Risk estimates using the PREDICT-PD algorithm were associated with the occurrence of sub-threshold parkinsonism, including bradykinesia and action tremor. The algorithm could also identify individuals whose motor examination experience a decline over time. © 2023 The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.

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parkinson,motor dysfunction,disease

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