Oxytocin Improves Intracerebral Hemorrhage Outcomes by Suppressing Neuronal Pyroptosis and Mitochondrial Fission.

Miaoxian Yang,Shuixiang Deng,Junliang Jiang,Mi Tian,Lei Xiao,Ye Gong

Stroke（2023）

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摘要

Intranasal application of OXT can ameliorate neurological deficits and alleviate neural pyroptosis, inflammation, and excessive mitochondrial fission via OXTR/p-PKA/DRP1 signaling pathway after ICH. Thus, OXT administration may be a potential therapeutic strategy to improve the prognosis of ICH.

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oxytocin,intracerebral hemorrhage outcomes,intracerebral hemorrhage,neuronal pyroptosis

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