Perioperative Administration of Pregabalin and Esketamine to Prevent Chronic Pain After Breast Cancer Surgery: A Randomized Controlled Trial.

Miao Wang, Hua-Ping Xiong,Kai Sheng,Xing-Bing Sun,Xiao-Qian Zhao,Qing-Ren Liu

Drug design, development and therapy（2023）

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摘要

Combined perioperative oral pregabalin and postoperative esketamine effectively prevented chronic pain after breast cancer surgery, improved acute postoperative pain, and reduced postoperative opioid consumption.

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关键词

pregabalin, esketamine, chronic pain, breast cancer surgery

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