PFKFB2 is a favorable prognostic biomarker for colorectal cancer by suppressing metastasis and tumor glycolysis.

Furong Liu,Xiaoli Wei,Zhanhong Chen,Yanxing Chen,Peishan Hu,Ying Jin

Journal of cancer research and clinical oncology（2023）

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摘要

PFKFB2 expression is downregulated in CRC tissues and associated with worse survival for CRC patients. PFKFB2 could inhibit metastasis and the malignant progression of CRC cells by suppressing EMT and glycolysis.

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关键词

Colorectal cancer, Prognosis, PFKFB2, Glycolysis, Metastasis

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