Comprehensive genetic analyses of childhood acute leukemia in Iraq using next-generation sequencing.

Lika'a Fasih Y Al-Kzayer, Raghad M Saeed,Hasanein Habeeb Ghali,Miyuki Tanaka,Mazin F Al-Jadiry,Safa A Faraj,Salma A Al-Hadad,Hussam M Salih Al Abdullah, Athar A Majeed, Ali Omer Qadir,Dana Ahmed Abdullah,Kani Dlawar Noori,Zheyan Mohammed Hama, Abdulrahman A Muhsin,Adnan Anwer Al-Doski,Yasir S Al-Agele,Abduladheem H Malallah,Khalid S Al-Badrani,Asmaa M A Khaleel,Minoru Kamata,Motoharu Hamada,Seiji Kojima,Yozo Nakazawa,Yusuke Okuno

Translational pediatrics（2023）

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摘要

Apart from disclosing the high frequency of , NGS confirmed our previous finding of recurrent mutations in Iraqi childhood acute leukemia. Our results suggest that the biology of Iraqi childhood acute leukemia is in part characteristic, where the war-aftermath environment or geography might play a role.

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关键词

childhood acute leukemia,comprehensive genetic analyses,next-generation

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