LINC00638/hsa-miR-29b-3p axis-mediated high expression of CDCA4 correlates with tumor immune infiltration and hepatocellular carcinoma progression.

The low expression of CDCA4 significantly improves the prognosis of LIHC patients, and CDCA4 is a potential new biomarker for LIHC prognosis prediction. CDCA4-mediated LIHC carcinogenesis may involve tumor immune evasion and anti-tumor immunity. LINC00638/hsa-miR-29b-3p/CDCA4 should be a potential regulatory pathway in LIHC, and these findings provide a new perspective for the development of anti-cancer strategies in LIHC.