Comparative Analysis of Apigenin-3 Acetate versus Apigenin and Methyl-Prednisolone in Inhibiting Proliferation and Gene Expression of Th1 Cells in Multiple Sclerosis.

Neda Kasiri,Seyed Mostafa Ghannadian,Reza Hosseini,Leila Ahmadi,Mahshid Rahmati,Fereshteh Ashtari,Abbasali Pourazar,Nahid Eskandari

Cell journal（2023）

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摘要

Our findings suggested that Api may have anti-inflammatory properties, possibly by inhibiting proliferation of IFN-producing Th1 cells. Moreover, comparative immunomodulatory effects were found for the acetylated version of apigenin-3-acetate versus Api and methyl-prednisolone-acetate.

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关键词

apigenin,apoptosis,multiple sclerosis,proliferation,th1

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