Targeting BET Proteins Decreases Hyaluronidase-1 in Pancreatic Cancer.

Krishan Kumar,Deepak Kanojia,David J Bentrem,Rosa F Hwang,Jonathan P Butchar,Susheela Tridandapani,Hidayatullah G Munshi

Cells（2023）

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摘要

Our results demonstrate the pro-tumorigenic role of HYAL1 and identify the role of BRD2 in the regulation of HYAL1 in PDAC. Overall, these data enhance our understanding of the role and regulation of HYAL1 and provide the rationale for targeting HYAL1 in PDAC.

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pancreatic cancer,proteins

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