Exploring the effect and mechanism of Haizao Yuhu decoction containing three variants of glycyrrhiza on goiter using an integrated strategy of network pharmacology and RNA sequencing.
Journal of ethnopharmacology(2023)
摘要
This study confirmed the definite effect of the three HYDs in the treatment of goiter, and HYD-U was found to be more effective. The three HYDs inhibited angiogenesis and cell proliferation in goiter tissue by inhibiting the PI3K-Akt signaling pathway.
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关键词
Haizao Yuhu decoction, Three species of glycyrrhiza, Goiter, Network pharmacology combined with RNA-Seq, PI3K-Akt pathway
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