Higher versus lower blood pressure targets after cardiac arrest: systematic review with individual patient data meta-analysis.

Ville Niemelä,Faiza Siddiqui,Koen Ameloot,Matti Reinikainen,Johannes Grand,Johanna Hästbacka,Christian Hassager, Jesper Kjaergard,Anders Åneman,Marjaana Tiainen,Niklas Nielsen,Markus Harboe Olsen,Caroline Kamp Jorgensen,Johanne Juul Petersen,Josef Dankiewicz,Manoj Saxena,Janus C Jakobsen,Markus B Skrifvars

Resuscitation（2023）

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摘要

Targeting a higher MAP compared to a lower MAP is unlikely to reduce mortality or improve neurologic recovery after CA. Only a large treatment effect above 25% (RR<0.75) could be excluded, and future studies are needed to investigate if relevant but lower treatment effect exists. Targeting a higher MAP was not associated with any increase in adverse effects.

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关键词

Cardiac arrest,Target,Blood pressure,Meta-analysis,Systematic review

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