Optimising prednisolone or prednisone replacement in adrenal insufficiency.

Angelica Sharma,Katharine Lazarus,Deborah Papadopoulou,Hemanth Prabhudev,Tricia Tan,Karim Meeran,Sirazum Choudhury

Endocrine connections（2023）

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摘要

This is the largest evaluation of oral prednisolone pharmacokinetics in humans. Low dose prednisolone of 2-4mg is safe and effective in most patients with AI. Doses can be titrated with either 4-hour, 6-hour, or 8-hour single timepoint drug levels.

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关键词

adrenal insufficiency,prednisone replacement,prednisolone

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