Clinical, histopathological and molecular features of dedifferentiated melanomas: An EORTC Melanoma Group Retrospective Analysis.
European journal of cancer (Oxford, England : 1990)（2023）
摘要
Our study further highlights that DedM represents a real diagnostic challenge. While MS and genomic CNP may help pathologists to diagnose DedM, we provide proof-of-concept that dedifferentiation in melanoma is frequently associated with epigenetic modifications.
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关键词
Dedifferentiated melanoma, Epigenetics, DNA methylation, Copy number profiling
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