Timing of Cefuroxime Surgical Antimicrobial Prophylaxis and Its Association With Surgical Site Infections.

Rami Sommerstein,Nicolas Troillet,Stephan Harbarth,Marlieke E A de Kraker,Danielle Vuichard-Gysin,Stefan P Kuster,Andreas F Widmer

JAMA network open（2023）

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摘要

In this cohort study, administration of cefuroxime SAP closer to the incision time was associated with significantly lower odds of SSI, suggesting that cefuroxime SAP should be administrated within 60 minutes prior to incision, and ideally within 10 to 25 minutes.

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关键词

cefuroxime surgical antimicrobial prophylaxis,surgical site infections

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