Synthesis and crystal structure of 2-[(2,3,5,6-tetrafluoropyridin-4-yl)amino]ethyl methacrylate

Acta crystallographica. Section E, Crystallographic communications(2023)

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摘要
In the title compound, C11H10F4N2O2, the conformation about the N-C-C-O bond is gauche [torsion angle = 61.84 (13)degrees]. In the crystal, N-H center dot center dot center dot O hydrogen bonds link the molecules into [010] chains, which are cross-linked by C-H center dot center dot center dot F and C-H center dot center dot center dot pi contacts. Hirshfeld surface analysis was conducted to aid in the visualization of these various influences on the packing. This analysis showed that the largest contribution to the surface contacts arises from F center dot center dot center dot H/H center dot center dot center dot F interactions (35.6%), followed by O center dot center dot center dot H/H center dot center dot center dot O (17.8%) and H center dot center dot center dot H (12.7%).
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关键词
crystal structure,perfluoropyridine,C-H center dot center dot center dot F interaction
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