Half-life estimation of pertussis-specific maternal antibodies in (pre)term infants after in-pregnancy tetanus, diphtheria, acellular pertussis vaccination.

Several variables influence the decay speed of maternal antibodies. Both approaches have (dis)advantages, while the choice is secondary when assessing the half-life of pertussis-specific antibodies. Brief summary: We compared two approaches for estimating the half-life of vaccine-induced pertussis-specific maternal antibodies, focusing on the difference between preterm and term born infants, while also examining other variables. Both approaches yielded similar results, with preterm infants showing a higher half-life.