Editorial: Elimination of biliary atresia.

future research. The future research needed to fill the gap of knowledge include: the potential of genetic neonatal screening according to racial geographic known susceptibility genes, the outcome of BA if immune-modulatory therapy is instituted within the earliest 2-4 weeks, the role of enzyme replacement of missing enzymes as GSTM1, defining the protective gene against BA in Down syndrome patients, defining if this protective gene is amenable to gene therapy among the other children, the role of environmental control of aflatoxin contamination of foods, the role of abandoning milking of the umbilical cord at delivery, the ideal timing and type of immune modulatory medicine for BA. More insight in BA susceptibility, etiology, screening, management, natural history, treatment, transplantation challenges, outcome, burden and prevention is needed to plan BA eradication.