Clinical and Prognostic Factors in Patients with IgG4-Related Kidney Disease.

Anis Chaba,Arnaud Devresse,Vincent Audard,Jean Jacques Boffa,Alexandre Karras,Claire Cartery,Clément Deltombe,Jonathan Chemouny, Claudine Contamin, Cecille Courivaud,Simon Duquennoy, Hugo Garcia,Dominique Joly,Nabila Goumri, Guillaume Hanouna, Jean Michel Halimi,Emmanuelle Plaisier,Mohamed Hamidou,Cédric Landron,David Launay,Celine Lebas,Mathieu Legendre,Agathe Masseau,Alexis Mathian,Lucile Mercadal,Nathalie Morel, Prisca Mutinelli-Szymanski,Sylvain Palat,Jean-Loup Pennaforte,Marie Noelle Peraldi,Agnieszka Pozdzik,Nicolas Schleinitz,Olivier Thaunat,Dimitri Titeca-Beauport,Charlotte Mussini, Sonia Touati, Eric Prinz,Anne Laure Faller, Sarah Richter,Eve Vilaine,Sophie Ferlicot, Clarissa Von-Kotze,Julie Belliere,Jerome Olagne,Rafik Mesbah,Renaud Snanoudj,Mathilde Nouvier,Mikael Ebbo,Mohamad Zaidan

Clinical journal of the American Society of Nephrology : CJASN（2023）

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摘要

IgG4-related kidney disease predominantly affected middle-aged males and manifested as tubulointerstitial nephritis with potential glomerular involvement. Complement consumption and the number of organs involved were associated with a higher relapse rate, whereas first-line therapy with Rituximab was associated with lower. Patients with high serum IgG4 concentrations (≥5g/L) had more severe kidney disease.

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关键词

CKD, chronic nephropathy, clinical immunology, clinical nephrology, interstitial fibrosis

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