POLRMT over-expression is linked to WNT/beta-catenin signaling, immune infiltration, and unfavorable outcomes in lung adenocarcinoma patients.

Yongkang Huang,Yajuan Qian,Yufei Xing,Yongjian Pei,Beilei Zhang,Ting Li,Xue Pan,Anyuan Zhong, Juan Du,Tong Zhou,Minhua Shi

Cancer medicine（2023）

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摘要

POLRMT is over-expressed in LUAD, thereby impacting patient survival. It is also involved in WNT/beta-catenin signaling and may affect tumor infiltration.

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关键词

immune infiltration, lung adenocarcinoma, outcome, pathway, POLRMT, Wnt signal

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