Integrative bioinformatics and validation studies reveal KDM6B and its associated molecules as crucial modulators in Idiopathic Pulmonary Fibrosis.

Anning Chen,Zhun Sun,Donglin Sun,Meiying Huang,Hongwei Fang,Jinyuan Zhang,Guojun Qian

Frontiers in immunology（2023）

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摘要

Our findings suggest that molecules related to chromatin-modifying enzymes, primarily KDM6B, play a critical role in the pathogenesis and progression of IPF.

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关键词

Idiopathic Pulmonary Fibrosis,chromatin-modifying enzymes,disease biomarker,hub genes,gene ontology,drug molecule

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