Analytical validation of the 7-gene biosignature for prediction of recurrence risk and radiation therapy benefit for breast ductal carcinoma in situ .

David Dabbs,Karuna Mittal, Scott Heineman,Pat Whitworth,Chirag Shah,Jess Savala,Steven C Shivers,Troy Bremer

Frontiers in oncology（2023）

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摘要

The analytical performance of the PreludeDx DCISionRT molecular assays was high in representative formalin-fixed, paraffin-embedded breast tumor specimens. The DCISionRT test has been analytically validated and has been clinically validated in multiple peer-reviewed published studies.

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关键词

DCIS - breast ductal carcinoma in situ, DCIS biomarkers and morphogenetic mechanisms, radiation therapy, analytical validation, radiogenomics, immunohistochemistry, DCISionRT

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