Embracing nomograms: A leap in the dark for enhanced risk stratification in STEMI

Acute ST-segment elevation myocardial infarction (STEMI) and its sequelae contribute significantly to global morbidity and mortality. The extent of myocardial tissue injury due to STEMI strongly determines the risk of heart failure and mortality [ [1] Stone G.W. Selker H.P. Thiele H. Patel M.R. Udelson J.E. Ohman E.M. et al. Relationship between infarct size and outcomes following primary PCI: patient-level analysis from 10 randomized trials. J. Am. Coll. Cardiol. 2016; 67: 1674-1683 Crossref PubMed Scopus (395) Google Scholar ]. Detailed assessment of the severity of myocardial tissue injury is thus useful for individualized risk stratification [ 1 Stone G.W. Selker H.P. Thiele H. Patel M.R. Udelson J.E. Ohman E.M. et al. Relationship between infarct size and outcomes following primary PCI: patient-level analysis from 10 randomized trials. J. Am. Coll. Cardiol. 2016; 67: 1674-1683 Crossref PubMed Scopus (395) Google Scholar , 2 Reindl M. Holzknecht M. Tiller C. Lechner I. Schiestl M. Simma F. et al. Impact of infarct location and size on clinical outcome after ST-elevation myocardial infarction treated by primary percutaneous coronary intervention. Int. J. Cardiol. 2020; 301: 14-20 Abstract Full Text Full Text PDF PubMed Scopus (11) Google Scholar , 3 Jensch P.J. Stiermaier T. Reinstadler S.J. Feistritzer H.J. Desch S. Fuernau G. et al. Prognostic relevance of peri-infarct zone measured by cardiovascular magnetic resonance in patients with ST-segment elevation myocardial infarction. Int. J. Cardiol. 2022; 347: 83-88 Abstract Full Text Full Text PDF PubMed Scopus (4) Google Scholar ].