An Exome-Wide Study of Renal Operational Tolerance

Frontiers in medicine（2023）

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摘要

Rare protein coding variants are associated with operational tolerance in a sizable portion of patients. Our findings have important implications for a better understanding of immune tolerance in transplantation and other fields of medicine.ClinicalTrials.gov, identifier: NCT05124444.

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关键词

exome sequencing, renal transplantation, operational tolerance, NGAL, LCN2, Homer2, IQCH, primary cilium

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