Biomarkers detected in cord blood predict vaccine responses in young infants.

Carolyn H Baloh,Guglielmo M Venturi,Bernard M Fischer, Liane S Sadder,Julie J Kim-Chang,Cliburn Chan,Kristina De Paris,Li Yin,Grace M Aldrovandi,Maureen M Goodenow,John W Sleasman

Frontiers in immunology（2023）

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摘要

Sustained B cell immunity is highly influenced by early life immune dynamics beginning prior to birth. The findings provide important insights into how germinal center development shapes vaccine responses in healthy infants and provide a foundation for studies of conditions that impair infant immune development.

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vaccine responses,cord blood,young infants,biomarkers

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