Immunophenotypic expression profile of multiple myeloma cases at a tertiary hospital in Nairobi Kenya.
Frontiers in medicine(2023)
摘要
Cyclin D1 expression was congruent with previously reported studies. The frequency of CD56 and CD117 expression was lower than previously reported. This may be due to differences in disease biology between the study populations. Approximately half of cases were Ki-67 positive. Our data showed limited associations between the expression of studied markers and clinicopathologic variables. However, this could be attributed to the small study sample size. We would recommend further characterization of the disease in a larger prospective study with the inclusion of survival outcomes and cytogenetic studies.
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关键词
Multiple Myeloma, immunophenotype, CD56, CD117, Cyclin D1, Ki-67, Kenya
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