Assessment of causal associations among gut microbiota, metabolites, and celiac disease: a bidirectional Mendelian randomization study.

Ting Li,Yan Feng,Chun Wang,Tian Shi,Adilai Abudurexiti,Mengxia Zhang,Feng Gao

Frontiers in microbiology（2023）

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摘要

We investigated the causal relationships between gut microbiota, metabolites, and CD with two-sample MR. Our findings suggest several novel potential therapeutic targets for CD treatment. Further understanding of the underlying mechanism may provide insights into CD pathogenesis.

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关键词

celiac disease, gut microbiota, metabolites, Mendelian randomization analysis, causal effect

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