Dietary monosodium glutamate increases visceral hypersensitivity in a mouse model of visceral pain.

Bailey J A Brant,Yang Yu,Amal Abu Omar,Josue O Jaramillo Polanco,Cintya D Lopez Lopez,Nestor N Jiménez Vargas,Quentin Tsang, Abby McDonell, Kaede Takami,David E Reed,Alan E Lomax,Stephen J Vanner,Caroline J Tuck

Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society（2023）

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摘要

These findings demonstrate that repeated exposure to MSG in mice leads to sensitization of jejunal afferent nerves to acute ex vivo exposure to MSG. This may contribute to visceral hypersensitivity reported in response to MSG in patients with IBS.

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关键词

dietary monosodium glutamate,visceral hypersensitivity,visceral pain

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