Novel α-Trifluoromethyl Chalcone Exerts Antitumor Effects Against Prostate Cancer Cells.

Takafumi Shimada,Renato Naito,Ren Toriumi,Ryunosuke Nakagawa,Shuhei Aoyama,Taiki Kamijima,Hiroshi Kano,Suguru Kadomoto,Hiroaki Iwamoto,Hiroshi Yaegashi,Kouji Izumi,Yoshifumi Kadono,Hiroki Nakata,Yohei Saito,Kyoko Nakagawa-Goto,Atsushi Mizokami

Anticancer research（2023）

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摘要

YS71 exhibits antitumor activity by inducing apoptosis in PCa cells, including taxane-resistant cells. It could be a potential future therapeutic option for hormone- and chemotherapy-resistant PCa.

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关键词

Prostate cancer, alpha-trifluoromethyl chalcone, YS71, androgen receptor

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