Complete genome sequence of cnidium virus 2, a novel cytorhabdovirus isolated from Cnidium officinale in South Korea

Archives of virology(2023)

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摘要
High-throughput sequencing identified a cytorhabdovirus, tentatively named “cnidium virus 2” (CnV2), in Cnidium officinale , and Sanger sequencing confirmed the genome sequence. CnV2 is 13,527 nucleotides in length and contains seven open reading frames in the order 3′-N-P-3-4-M-G-L-5′, separated by intergenic regions. The full-length nucleotide sequence of CnV2 shares 19.4–53.8% identity with other known cytorhabdovirus genome sequences. The N, P, P3, M, G, and L proteins share 15.8–66.7%, 11–64.3%, 11.1–80.5%, 10.8–75.3%, 12.3–72.1%, and 20–72.7% amino acid sequence identity, respectively, with the cognate deduced protein sequences from known cytorhabdoviruses. CnV2 is related to other members of the genus Cytorhabdovirus , with sambucus virus 1 being the closest relative. Thus, CnV2 should be classified as a new member in the genus Cytorhabdovirus of the family Rhabdoviridae .
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cnidium virus,novel cytorhabdovirus,cnidium officinale,complete genome sequence
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