Antihypertensives in dementia: Good or bad for the brain?

Rachel Am Heutz,Ralf Wj Weijs,Rianne Aa de Heus,Jurgen Ahr Claassen

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism（2023）

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摘要

We discuss the current evidence for both benefit and harm of antihypertensive treatment in people with dementia. We conclude that there is a lack of evidence to support the claim that there is an increased risk of cerebral hypoperfusion with antihypertensive treatment in dementia, and that there is growing evidence which refutes this claim.

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Cerebral autoregulation, dementia, hypertension, orthostatic hypotension, side effects

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