Association of Antifolate Response Signature Status and Clinical Activity of Pemetrexed-Platinum Chemotherapy in Non-Small Cell Lung Cancer - The Piedmont Study.

Joel R Eisner,Gregory M Mayhew,James M Davison,Kirk D Beebe,Yoichiro Shibata,Yuelong Guo,Carol Farhangfar,Farhang Farhangfar,Joshua M Uronis, Jeffrey M Conroy,Michael V Milburn,David Neil Hayes,Kathryn F Mileham

Clinical cancer research : an official journal of the American Association for Cancer Research（2023）

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摘要

AF-PRS identified a significant population of patients with extended PFS and/or clinical response following PMX-PDC treatment. AF-PRS may be a useful diagnostic test for patients indicated for systemic chemotherapy, especially when determining the optimal PDC regimen for locally advanced disease.

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